| 前药--一种可靠的口服结肠靶向释药系统 |
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| 引用本文： | 孙晓飞,王淑萍. 前药--一种可靠的口服结肠靶向释药系统[J]. 药学进展, 2004, 28(1): 19-22 |
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| 作者姓名： | 孙晓飞 王淑萍 |
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| 作者单位： | 苏州大学医学院药学系,江苏,苏州,215007 |
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| 摘 要： | 综述了近年来前药的发展状况，并评价了各类前药的特点和发展前景。前药技术作为一种可靠的口服结肠靶向释药系统，不仅能减少药物的口服剂量，降低副作用并且增加了药效。
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| 关 键 词： | 前药 口服结肠靶向释药系统 口服剂量 偶合物 |
| 文章编号： | 1001-5094(2004)01-0016-04 |
| 修稿时间： | 2004-06-17 |
Prodrugs:A Promising Oral Colon-specific Drug Delivery System |
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| SUN Xiao-fei,WANG Shu-ping. Prodrugs:A Promising Oral Colon-specific Drug Delivery System[J]. Progress in Pharmaceutical Sciences, 2004, 28(1): 19-22 |
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| Authors: | SUN Xiao-fei WANG Shu-ping |
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| Abstract: | Prodrugs as the approaches of colon-specific drugdcliver system can not only reduce the dose to be administered, but also decrease the side effects and improve the drug efficacy. Various prodrug techniques for oral colon-specific drug delivery system have been investigated in this review. |
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| Keywords: | Prodrug Oral colon-specific drug delivery system Conjugates |
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