Bile duct evaluation of potential living liver donors with Gd-EOB-DTPA enhanced MR cholangiography: Single-dose,double dose or half-dose contrast enhanced imaging |
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Authors: | Sonja Kinner Verena Steinweg Stefan Maderwald Arnold Radtke Georgios Sotiropoulos Michael Forsting Tobias Schroeder |
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Affiliation: | 1. Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Germany;2. Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen, Germany;3. Department of General Surgery, University Hospital Essen, Germany |
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Abstract: | IntroductionDetailed knowledge of the biliary anatomy is essential to avoid complications in living donor liver transplantation. The aim of this study was to determine the optimal dosage of Gd-EOB-DTPA for contrast-enhanced magnetic resonance cholangiography (ce-MRC) with reference to contrast-enhanced CT cholangiography (ce-CTC).Materials and methods30 potential living liver donors (PLLD) underwent both ce-CTC and ce-MRC. Ten candidates each received single, double or half-dose Gd-EOB-DTPA. Ce-MRC images with and without inversion recovery pulses (T1w ± IR) were acquired 20–30 min after intravenous contrast injection. Image data was quantitatively and qualitatively reviewed by two radiologists based on a on a 5-point scale. Data sets were compared using a Mann–Whitney-U-test or Wilcoxon-rank-sum-test. Kappa values were also calculated.ResultsAll image series provided sufficient diagnostic information both showing normal biliary anatomy and variant bile ducts. Ce-CTC showed statistically significant better results compared to all ce-MRC data sets. T1w MRC with single dose Gd-EOB-DTPA proved to be superior to half and double dose in subjective and objective evaluation without a statistically significant difference.ConclusionsCe-MRC is at any dosage inferior to ce-CTC. As far as preoperative planning of bile duct surgery is focused on the central biliary anatomy, ce-MRC can replace harmful ce-CTC strategies, anyway. Best results were seen with single dose GD-EOB-DTPA on T1w MRC+IR. |
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Keywords: | Living liver transplantation MR cholangiography Gd-EOB-DTPA, |
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