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Successful treatment of osseous blastomycosis without pulmonary or disseminated disease and review of the literature |
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| Authors: | Shandra R. Day David B. Weiss Kevin C. Hazen Christopher C. Moore |
| Affiliation: | 1. Division of Infectious Diseases & International Health, University of Virginia Health System, Charlottesville, VA;2. Department of Orthopedic Surgery, University of Virginia Health System, Charlottesville, VA;3. Clinical Microbiology Laboratory, Department of Pathology, Duke University, Durham, NC |
| Abstract: | Blastomycosis commonly occurs following inhalation of Blastomyces dermatitidis conidia causing a pulmonary infection and can disseminate to extrapulmonary sites. Osseous involvement primarily results from hematogenous spread, but in rare cases, direct inoculation can occur. We describe a case of osseous blastomycosis without pulmonary or disseminated disease successfully treated with posaconazole. |
| Keywords: | Blastomycosis Orthopedic infection Cutaneous inoculation |
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