Looking back and looking forward: Normal lung growth and the pathophysiological consequences of ‘misplaced’ growth in disease

This tribute is dedicated to Lynne M. Reid, M.D. It is a précis of a special lecture given by her at the 4th International Workshop for Pulmonary Functional Imaging, held at Harvard Medical School in Boston, Sept. 24–26, 2009. Dr. Reid's remarks include those of an historical nature as well as thematic presentations of the growth and remodeling of pulmonary airways and vessels both physiologically and pathophysiologically. The role of hyperoxia and hypoxia in adaptive and pathological settings were emphasized. The theme throughout Dr. Reid's lecture was the relationship between structure and function, and how each serves and is consequent on the other.