乳头状肾细胞癌的诊断和治疗

目的；提高乳头状肾细胞癌的诊治水平。方法：8例均作影像学检查，IVU示患侧肾脏外形增大；CT示患侧肾脏有类圆形，界限清楚，中心有肿瘤坏死引起的代密度灶。8例患者均接受肾癌根治术，其中2例经腹腔途径，6例经11肋间切口。结果：随访4-60个月。除1例于术后13个月死于颅内转移外，其余均生存。结论：乳头状肾细胞癌是较罕见的肾细胞肿瘤，其形态学和遗传学与非乳头状肾细胞癌有明显不同；其确诊有赖于影像学检查，典型病理检查及分子遗传学特征分析；治疗仍以手术为主。

Papillary renal cell carcinoma(Report of 8 cases)

Purpose: To improve the diagnosis and treatment of renal papillary renal cell carcinoma (PRCC). Methods: Clinical data of 8 cases of patients with PRCC were reviewed retrospectively and analyzed in the light of literature. Results: All 8 cases underwent radical nephrectomy. Follow up of 4 to 60 months demonstrated that 1 case died of encephalic metastasis 13 months after operation and the other 7 cases have been living without tumor. Conclusions; PRCC is a unusual renal cell carcinoma. Morphologic, cytochemical, and genotypic features of PRCC are different to that of non-PRCC. Definite diagnosis depends on imaging examination, the typical pathological and cytochemical, and genotypic features. Open operation is the treatment of choice.