Ultrasound Parameters for Human Osteoarthritic Subchondral Bone ex Vivo: Comparison with Micro-Computed Tomography Parameters |
| |
| Authors: | Wataru Kiyan Yasuaki Nakagawa Akira Ito Hirotaka Iijima Kohei Nishitani Momoko Tanima-Nagai Shogo Mukai Junichi Tajino Shoki Yamaguchi Akihiro Nakahata Jue Zhang Tomoki Aoyama Hiroshi Kuroki |
| |
| Affiliation: | 2. Researching Department, Furuno Electric Company, Ltd., Nishinomiya, Japan;3. Department of Orthopaedic Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan;4. Department of System Design Engineering, Keio University, Yokohama, Japan;5. Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan |
| |
| Abstract: | The aim of this study was to identify ultrasound parameters reflecting subchondral porosity (Po), subchondral plate thickness (Tpl) and bone volume fraction at the trabecular bone region (BV/TVTb). Sixteen osteoarthritic human lateral femoral condyles were evaluated ex vivo using a 15-MHz pulsed-echo ultrasound 3-D scanning system. The cartilage–subchondral bone (C-B) surface region (layer 1) and inner subchondral bone region (layer 2) were analyzed; we newly introduced entropy (ENT) and correlation (COR) of ultrasound texture parameters of the parallel (x) or perpendicular (z) direction to the C-B interface for this analysis. Po, Tpl and BV/TVTb were evaluated as reference measurements using micro-computed tomography. ENTL1x (ENT of layer 1, x-direction) and ENTL1z were significantly correlated with Po (both r values?=?0.58), CORL2x with Tpl (r?=?–0.73) and CORL2z with BV/TVTb (r?=?–0.66). These are efficient indicators of the characteristics of osteoarthritis-related subchondral bone; the other texture parameters were not significant. |
| |
| Keywords: | Osteoarthritis Subchondral bone Micro-computed tomography Ultrasound Texture parameter Porosity Thickness Bone volume fraction Cartilage |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
