Association of idiopathic retroperitoneal fibrosis, rapidly progressive glomerulonephritis and antiproteinase 3 antineutrophil cytoplasmic antibodies (anti PR3-ANCA) |
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Authors: | Martínez-Odriozola P Gutiérrez-Macías A Moina Eguren I Arrieta Lezama J |
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Affiliation: | Internal Medicine Department, Hospital de Basurto, Bilbao, Spain. |
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Abstract: | We report a case of idiopathic retroperitoneal fibrosis and rapidly progressive glomerulonephritis with serum antiproteinase 3 antineutrophil cytoplasmic antibodies (anti-PR3-ANCA), without clinical or histological signs of Wegener's granulomatosis, in a 46-year-old man. Our case and previously reported cases showing the same association support the hypothesis that the association is not fortuitous, but reflects a common immunological mechanism. |
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