| 羟脯氨酸及氨基己糖作为氯乙烯单体生物监测指标的探讨 |
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| 引用本文： | 付贵生,管康.羟脯氨酸及氨基己糖作为氯乙烯单体生物监测指标的探讨[J].工业卫生与职业病,1997,23(2):78-80. |
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| 作者姓名： | 付贵生 管康 |
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| 作者单位： | 化工部化工劳动保护研究所!青岛市延安三路218号，2660071，化工部化工劳动保护研究所!青岛市延安三路218号，2660071，化工部化工劳动保护研究所!青岛市延安三路218号，2660071，化工部化工劳动保护研究所!青岛市延安三路218号，2660071，化工部化工劳动保护研究所!青岛市延安三路 |
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| 摘 要： | 工人长期接触氯乙烯单体（ＭＶＣ）可以致氯乙烯病。为了筛选生物监测指标，我们给大鼠经肺吸入不同浓度的氯乙烯单体，经过６周和８周后监测多项指标，结果发现高浓度组中羟脯氨酸和氨基己糖均明显高于对照组，同时在人群中也得到证实。
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| 关 键 词： | 氯乙烯单体 生物监测 羟脯氨酸 氨基己糖 |
ABOUT TAKING HYDROXYPROLINE AND HEXOSAMINE AS BIOMONITORING INDICATORS OF VINYL CHLORIDE MONOMER EXPOSURE |
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| Fu Guisheng et al.ABOUT TAKING HYDROXYPROLINE AND HEXOSAMINE AS BIOMONITORING INDICATORS OF VINYL CHLORIDE MONOMER EXPOSURE[J].Industrial Health and Occupational Diseases,1997,23(2):78-80. |
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| Authors: | Fu Guisheng |
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| Abstract: | Long-term exposure to vinyl chloride monomer mad cause so called vinyl chloride disease. Inorder to screen more specific and sensitive biomonitoring indicators for its exposure, different dosesof vinyl chloride monomer were given to rats by inhalation for 6 and & weeks. Afterwards, variouscomponents were monitored. The results showed that the concentrations of hydroxyproline andhexosamine are obviously higher in high dose group than those in controls, which is also verified inexposed workers. |
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| Keywords: | Biomonitoring indicator Hydroxyproline Hexosamine |
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