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| 黄药的化学成分研究 | |
| 引用本文： | 吴小明,裴月湖,周金云.黄药的化学成分研究[J].药学学报,2005,40(12):1127-1130. |
| 作者姓名： | 吴小明 裴月湖 周金云 |
| 作者单位： | 1. 中国医学科学院、中国协和医科大学,药物研究所,北京,100050;沈阳药科大学,辽宁,沈阳,110016 2. 沈阳药科大学,辽宁,沈阳,110016 3. 中国医学科学院、中国协和医科大学,药物研究所,北京,100050 |
| 基金项目： | 核磁共振谱、质谱、红外光谱和紫外光谱由中国医学科学院药物研究所分析测试中心代测. |
| 摘 要： | 目的研究黄药(Rhamnus crenatus)的化学成分。方法用硅胶正相色谱及聚酰胺色谱技术进行分离纯化，根据理化性质、光谱数据进行结构鉴定。结果从黄药地上部分的95%乙醇提取物的乙酸乙酯部分中分离得到了5个化合物：黄药苷(1)、torachrysone (2)、大黄素(3)、大黄素-1-O-β-D-葡糖苷(4)和β-谷甾醇(5)。结论化合物1为新化合物，其余化合物均为首次从该植物中分离得到。 |
| 关 键 词： | 黄药 色酮类 黄药苷 |
| 文章编号： | 0513-4870（2005）12-1127-04 |
| 收稿时间： | 2005-04-19 |
| 修稿时间： | 2005-04-19 |
Chemical constituents of the aerial parts of Rhamnus crenatus |
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| WU Xiao-ming,PEI Yue-hu,ZHOU Jin-yun.Chemical constituents of the aerial parts of Rhamnus crenatus[J].Acta Pharmaceutica Sinica,2005,40(12):1127-1130. | |
| Authors: | WU Xiao-ming PEI Yue-hu ZHOU Jin-yun |
| Institution: | 1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China; 2. Shenyang Pharmaceutical Unirersity, Shenyang 110016, China |
| Abstract: | AIM: To study chemical constituents of the aerial parts of Rhamnus crenatus sieb. et zucc. METHODS: The chemical constituents were isolated by chromatographic methods and their structures were elucidated on the basis of spectral analysis. RESULTS: Five compounds were isolated and their structures were identified as crenatoside (1), torachrysone (2), emodin (3), emodin-1-O-beta-D-glucopyranoside (4) and beta-sitosterol (5) respectively. CONCLUSION: Compound 1 is a new compound and the others were isolated from Rhamnus crenatus for the first time. |
| Keywords: | Rhamnus crenatus chromone crenatoside |
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