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Acute Hyperglycemia Worsens Hepatic Ischemia/Reperfusion Injury in Rats |
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| Authors: | Matthias Behrends Graciela Martinez-Palli Claus U. Niemann Sara Cohen Rageshree Ramachandran Ryutaro Hirose |
| Affiliation: | (1) Department of Anesthesia and Perioperative Care, University of California San Francisco, 533 Parnassus Avenue, U 368n, San Francisco, CA 94143-0648, USA;(2) Servicio de Anestesiologia, Hospital Clinic de Barcelona, Universitat de Barcelona, Barcelona, Spain;(3) Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA, USA;(4) Department of Pathology, University of California San Francisco, San Francisco, CA, USA |
| Abstract: | Background/AimsAcute hyperglycemia is known to worsen ischemia/reperfusion (I/R) injury following myocardial infarction and stroke. We investigated whether acute hyperglycemia worsens injury and amplifies the inflammatory response evoked by hepatic I/R. |
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