|
|||||
|
|
Iliac bone histomorphometry in children with newly diagnosed inflammatory bowel disease |
|
| Authors: | L. M. Ward F. Rauch M. A. Matzinger E. I. Benchimol M. Boland D. R. Mack |
| Affiliation: | 1. Department of Pediatrics, Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada 2. Genetics Unit, Shriners Hospital for Children, McGill University, Montréal, Quebec, Canada 3. Director, Pediatric Bone Health Clinical and Research Programs, Children’s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, Ontario, K1H 8L1, Canada |
| Abstract: | SummaryChildren with inflammatory bowel disease (IBD) manifest low bone mass; the cause remains unclear. We performed transilial bone biopsies in 20 IBD children at diagnosis and found a mild cortical bone deficit and slow bone turnover. It is possible that low mechanical stimulation due to inadequate muscle mass contributes to the bone deficit. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |