Conservation of small-airway function by tacrolimus/cyclosporine conversion in the management of bronchiolitis obliterans following lung transplantation |
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| Authors: | Matthew P Revell FRCS Michael E Lewis FRCS Carol G Llewellyn-Jones MD FRCP Ian C Wilson MD FRCS Robert S Bonser MRCP FRCS |
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| Institution: | Department of Cardiothoracic Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom. |
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| Abstract: | We studied serial lung function in 11 patients with bronchiolitis obliterans syndrome who were treated with tacrolimus conversion following lung or heart-lung transplantation. Our results show that tacrolimus conversion slows the decline of lung function in bronchiolitis obliterans syndrome. The attenuation continues for at least 1 year following conversion. |
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