超声组织定征在心血管疾病诊断中的应用

超声组织定征(Ultrasonic Tissue Characterization,UTC)技术是通过检测组织的声学参数来定量描述正常和病理组织的物理(声学)特性。研究表明,背向散射积分作为组织定征的参数,可以识别缺血心肌、顿抑心肌、梗死心肌、左心室心肌肥厚及心脏移植排斥反应,评价和分析系统性疾病如糖尿病等引起的弥漫性心肌受累的状态、心腔内血栓和动脉斑块的成份等。因而UTC技术具有很大的临床价值和发展潜力,将成为常规超声心动图诊断的辅助手段。本文就超声组织定征技术在心血管疾病诊断中的应用及进展作一综述。

Ultrasonic backscatter tissue characterization in cardiac diagnosis

Ultrasonic tissue characterization is based on the principle of ultrasonic backscatter, and quantitatively describes the physical (acoustic) characteristics of normal and abnormal tissue by detecting the acoustic parameters. The development of realtime two-dimensional integrated backscatter imaging has made feasible clinical investigations of ultrasonic tissue characterization, including detection of ischemic myocardium, stunned myocardium, infarcted myocardium, left ventricular hypertrophy, detection of cardiac ailograft rejection , and study of diffuse myocardial involvement with systemic diseases such as diabetes mellitus and composition of thrombus. Ultrasonic tissue characterization has shown the potential to yield information about structural and functional properties of cardiovascular tissue.