| 中医辨证施治胆管癌用药规律及药理学研究进展 |
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| 引用本文： | 白金钊,贾立群,陈冬梅,刘闰平.中医辨证施治胆管癌用药规律及药理学研究进展[J].中草药,2023,54(24):8228-8240. |
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| 作者姓名： | 白金钊 贾立群 陈冬梅 刘闰平 |
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| 作者单位： | 北京中医药大学中药学院, 北京 100029;中日友好医院 中西医结合肿瘤内科, 北京 100029 |
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| 基金项目： | 北京市科技新星计划交叉学科合作课题（Z211100002121167） |
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| 摘 要： | 胆管癌是由胆汁淤积、胆管结石、肝硬化、自身免疫性肝病、肝炎等前置病变恶化发展而来的重大疾病。通过对临床诊疗中常见的5种胆管癌中医证型进行总结，分析各证型胆管癌的临床常用方药。通过频次与用药规律分析，筛选出关键中药，并根据其功效归纳为疏肝健脾、清热祛湿与其他功效中药，并从现代药理学角度总结了相关研究进展。通过系统梳理胆管癌辨证论治的用药规律，为胆管癌临床诊疗和抗胆管癌中药创新药物研发提供参考。
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| 关 键 词： | 胆管癌 中医证候 疏肝健脾 清热祛湿 肝郁脾虚证 肝胆湿热证 湿热蕴蒸证 热毒炽盛证 脾阳虚衰证 |
| 收稿时间： | 2023/6/4 0:00:00 |
Research progress on medication patterns and pharmacology of traditional Chinese medicine for treating cholangiocarcinoma based on syndrome differentiation |
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| BAI Jin-zhao,JIA Li-qun,CHEN Dong-mei,LIU Run-ping.Research progress on medication patterns and pharmacology of traditional Chinese medicine for treating cholangiocarcinoma based on syndrome differentiation[J].Chinese Traditional and Herbal Drugs,2023,54(24):8228-8240. |
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| Authors: | BAI Jin-zhao JIA Li-qun CHEN Dong-mei LIU Run-ping |
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| Institution: | School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China;Oncology Department of Integrated Traditional Chinese and Western Medicine, China-Japan Friendship Hospital, Beijing 100029, China |
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| Abstract: | |
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| Keywords: | cholangiocarcinoma traditional Chinese medicine syndrome harmonizing liver and invigorating spleen clearing heat and eliminating dampness liver hyperactivity with spleen deficiency pattern damp heat in liver and gallbladder pattern damp heat accumulation pattern exuberance of toxic heat pattern spleen yang deficiency syndrome |
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