脑电图结合CT预测一氧化碳中毒迟发性脑病

探讨预测一氧化碳中毒迟发性脑病的检查方法，以及高压氧治疗时间与脑病的关系。方法用脑电地形图和头颅ＣＴ分析２９３例一氧化碳中毒不同程度、不同高压氧治疗时间与一氧化碳中毒迟发性脑病发生的关系。结果中重度中毒脑电地形图与轻度中毒异常率比较差异显。

Prediction of delayed encephalopathy following acute carbon monoxide poisoning by brain electric activity mapping and CT

AIM To explore a new way to predict delayed encephalopathy following acute carbon monoxide poisoning and to investigate the correlation between the time of hyperbaric oxygen treatment and encephalopathy. METHODS 293 patients with carbon monoxide poisoning of various degrees and hyperbaric oxygen treatment duration were analyzed by using brain electric activity mapping (BEAM) and head CT. RESULTS By using BEAM, a significant difference was observed in the abnormality rate between moderate / severe cases and mild cases ( P <0.05). Early BEAM and head CT indicated a significant increase of encephalopathy incidence in abnormal patients compared with that in normal patients ( P <0.01). CONCLUSION Delayed encephalopathy following carbon monoxide poisoning is related to the degree of poisoning and premature termination of hyperbaric oxygen treatment. BEAM is more sensitive than head CT while the latter is more specific than the former. BEAM can be used in the screening and treatment of encephalopathy whereas CT can be used in the evaluation of treatment effect.