MRI和~1H-MRSI在颞叶癫痫中的对比研究 |
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引用本文: | 戴辉,赖力,周翰,兰琦,李忠,付凯.MRI和~1H-MRSI在颞叶癫痫中的对比研究[J].四川医学,2012,33(2):348-350. |
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作者姓名: | 戴辉 赖力 周翰 兰琦 李忠 付凯 |
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作者单位: | 1. 遵义医学院附属医院放射科,贵州遵义,563003 2. 四川省人民医院放射科,四川成都,610072 |
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摘 要: | 目的探讨磁共振(MRI)和氢质子磁共振波谱成像(’H-MRSI)对颞叶癲痫(TLE)的定位诊断价值。方法选择15例经临床表现和脑电图诊断的颞叶癫痫患者和15例健康志愿者为研究对象,一次性行MRI检查及两侧海马结构的1H-MRSI检查。结果 MRI发现5例患者单侧海马硬化。1H-MRS可对8例患者进行定侧诊断,其中3例有双侧颞叶病变。将两种检查方法结合起来可对10例准确定位。结论1H-MRS对颞叶癫痫定侧敏感性高于MRI,MRI诊断海马硬化特异性较高。两者相结合可提高术前定位的准确率。
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关 键 词: | 颞叶癫痫 定位诊断 磁共振成像 磁共振波谱成像 |
Comparative studies on temporal lobe epilepsy by MRI and 1H-MRSI |
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Institution: | DAI Hui1,LAI Li2,ZHOU Han2,et al.1.Affiliated Hospital of Zunyi Medical College,Zunyi,Guizhou 563003;2.The People′s Hospital of Sichuan,Chengdu,Sichuan 610072,China |
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Abstract: | Objective To evaluate the value of MRI and 1H-MRSI in the lacalization diagnosis(LD)of temporal lobe epilepsy(TLE).Methods 15 selected patients with TLE verified by clinical manifestations and diagnosis of EEG and 15 healthy volunteers were studied.One-time conventional MRI and bilateral hippocampus 1H-MRSI inspection.Results 5 of these patients showed unilateral hippocampus sclerosis.1H-MRSI of hippocampal was positive in 8 cases,3 cases showing bilateral abnormalities,combination of the two methods can accurate positioning of locases.Conclusion 1H-MRS was more sensitive than MRI in lateralizing seizure origin,and bilateral lesions can be foung but MRI was more specific than 1H-MRS.Combination of MRS with MRI can improve the accuracy ratio of the localization diagnosis. |
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Keywords: | temporal lobe epilepsy localization diagnosis magnetic resonance spectroscopy magnetic resonance imaging |
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