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腹腔镜脾切除术治疗特发性血小板减少性紫癜15例
引用本文:张建成,吴刚,李红光,孙培春,翟保平. 腹腔镜脾切除术治疗特发性血小板减少性紫癜15例[J]. 中国医药科学, 2012, 0(18): 25+42
作者姓名:张建成  吴刚  李红光  孙培春  翟保平
作者单位:河南省人民医院普外科
基金项目:2012年河南省基础研究项目(122300410057)
摘    要:目的研究针对难治性特发性血小板减少性紫癜的腹腔镜脾切除术治疗的可行性。方法 15例ITP患者术前均为皮质激素治疗无效或皮质激素依赖,均在腹腔镜下顺利完成脾切除术,分析比较手术前后患者的血小板计数情况。结果 15例ITP患者LS手术均获成功,术中失血30~120mL,手术时间60~150min。术后1年完全显效10例,2例部分显效,总有效率为80.0%(12/15)。结论对激素治疗无效或激素依赖的ITP患者,行腹腔镜脾切除术安全有效,可作为首选治疗方法。

关 键 词:特发性血小板减少性紫癜  腹腔镜  脾切除术

15 cases of laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura
ZHANG Jiancheng,WU Gang,LI Hongguang,SUN Peichun,ZHAI Baoping. 15 cases of laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura[J]. China Medicine and Pharmacy, 2012, 0(18): 25+42
Authors:ZHANG Jiancheng  WU Gang  LI Hongguang  SUN Peichun  ZHAI Baoping
Affiliation:Department of General Surgery, People’s Hospital of Henan Province,Zhengzhou 450003, China
Abstract:Objective To study the efficacy of laparoscopic splenectomy in treatment of idiopathic thrombocytopenic purpura resistant to medical management. Methods 15 patients with ITP underwent laparoscopic splenectomy.The data of preoperative and postoperative platelet counts were analyzed retrospectively. Results Operations were succed in 15 cases. Operation time was (30 ~ 120) min,blood loss in operation was (30~120) mL. After 1 years, 10 cases were markedly effective, 2 cases effective, the total effective rate was 80% (12/15). Conclusion Laparoscopic splenectomy is a relatively safe and effective method for treatment of ITP.
Keywords:Idiopathic thrombocytopenic purpura  Laparoscopic  Splenectomy
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