血清抑制素B水平预测卵巢储备功能的临床价值

目的:探讨血清基础抑制素B水平与卵巢储备功能的关系及其临床价值。方法:将158例观察对象分为3组,卵巢早衰(POF)组73例,卵巢储备功能下降(DOS)组55例,卵巢功能正常组30例,分别观测其血清基础抑制素B(INHB)、雌二醇(E2)、促卵泡素(FSH)、卵巢基质血流阻力指数(RI)、窦卵泡计数(OVF)、卵巢直径(OVD)、症状积分值。结果:INHB水平在POF组及DOS组与正常组相比均有极显著性差异(P<0.001),POF组与DOS组相比也有显著性差异(P<0.05),且POF组

Clinical value of serum inhibin B in predicting ovarian function

Objective:To explore the clinical value of serum inhibin B in predicting ovarian function.Methods:One hundred and fifty eight women were divided into groups:73 patients with premature ovarian failure(POF) and 55 patients with decreasing ovarian store(DOS),while 30 normal women as the control group.The basal serum inhibin B(INHB),estradiol(E2),follicle stimulating hormone(FSH),resistance index(RI) of ovarian,ovary follicle(OVF),ovary diameter(OVD),and symptom point were detected.Results:Compared with the control group,the level of INHB decreased significantly in the POF group and DOS group(P<0.001),and INHB level of the POF group was significantly lower than that of DOS group(P<0.05).INHB level of serious group was significantly lower than mild group(P<0.01),and compared with the moderate,the level of INHB was significantly different in serious group and mild group(P<0.05).There was positive correlation among INHB and E2 and OVF(P<0.05).There was negative correlation among INHB and FSH,RI,symptom point(P<0.05).Conclusions:There is correlation between serum inhibin B and ovarian function.Serum inhibin B may offer scientific proof in predicting ovarian function.