| 志愿献血者中乙肝病毒感染状况的研究 |
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| 引用本文： | 贾文祥,牟家琬,何良修,蔡美英,姜大秀,王道若,李明远,杨树斌,雷幼导,陈正鹏.志愿献血者中乙肝病毒感染状况的研究[J].四川大学学报(医学版),1986(4). |
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| 作者姓名： | 贾文祥 牟家琬 何良修 蔡美英 姜大秀 王道若 李明远 杨树斌 雷幼导 陈正鹏 |
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| 作者单位： | 华西医大微生物学与免疫学教研室
(贾文祥，牟家琬，何良修，蔡美英，姜大秀，王道若，李明远)，中国原子能科学研究院
(杨树斌)，华西医大基础医学系同位素室
(雷幼导)，华西医大基础医学系同位素室(陈正鹏) |
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| 摘 要： | 从423例经RPHA确定为HBsAg阴性的献血员中,再用HBsAg-抗-HBs固相放射免疫双测定药盒复查,证实有15例(3.5％)献血员携带 HBsAg。用被动血凝抑制试验检测抗-HBc,发现 304例献血员中,有101例(33.2％)血清中含抗-HBc(滴度>1:100),其中有 8例(7.9％)HBsAg和抗-HBc同时为阳性。作者认为在筛选献血员时,应该用放射免疫等敏感性高的技术检测HBsAg,同时最好能辅以检测抗-HBc,以减少输血后肝炎。
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| 关 键 词： | 献血员 HBsAg 抗-HBc |
STUDIES ON DISTRIBUTION OF HBV INFECTION IN VOLUNTARY BLOOD DONORS |
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| Jia wenxiang,Mu Jiawan,Cai Meiying,He Liangxiu,Jiang Daxiu,Wang Daoruo,Li Mingyuan,Yang Shubin,Lei Youdao,Chen Zhengpeng.STUDIES ON DISTRIBUTION OF HBV INFECTION IN VOLUNTARY BLOOD DONORS[J].Journal of West China University of Medical Sciences,1986(4). |
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| Authors: | Jia wenxiang Mu Jiawan Cai Meiying He Liangxiu Jiang Daxiu Wang Daoruo Li Mingyuan Yang Shubin Lei Youdao Chen Zhengpeng |
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| Institution: | Jia wenxiang;Mu Jiawan;Cai Meiying;He Liangxiu;Jiang Daxiu;Wang Daoruo;Li Mingyuan;Yang Shubin;Lei Youdao;Chen Zhengpeng Department of Microbiology and Immunology Institute of Atomic Energy of China Laboratory of Isotopes |
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| Abstract: | Sera of 423 voluntary blood donorswere collected and found to be negativefor HBsAg by reverse passive haemag-glutination (RPHA).However,whenthese sera were retested by solid phaseradioimmuno - two - assay kit of HBsAg andanti-HBs (SPRIA),15(3.5%) were positivefor HBsAg.Also,all of 304 bloodsamples from blood donors were testedfor the presence of anti-HBc by immuneadherence haemagglutination inhbition, thepositive rate(anti-HBc titre>1:100)was 33.2%(101).Among these sera,8(7.9%) samplescontained both HBsAg and anti-HBc.Thisstudy emphasizes the fact that RPHA testalone is not good enough to screenblood donors and that voluntary blooddonors should be carefully screened byusing more sensitive rests so as toimprove the quality of donated bloodand prevent HBV infection and post-transfusion hepatitis. |
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| Keywords: | Blood donor HBsAg Anti-HBc |
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