幽门螺杆菌感染与肝源性胃病的关系

目的探讨幽门螺杆菌（Helicobacter pylori，Hp）感染与肝源性胃病的关系。方法慢性乙型肝炎患者265例，乙型肝炎后肝硬化患者263例，非慢性肝病患者158例，均行快速尿素酶试验及^14C-尿素呼气实验。结果慢性乙型肝炎、乙型肝炎后肝硬化及非慢性肝病对照组的Hp感染率分别为48．3％、41．8％和81．6％。肝源性溃疡Hp感染率为48．1％，而对照组消化性溃疡Hp阳性率为90．6％。结论慢性乙型肝病患者的Hp感染率与对照组相比较低，Hp感染不是肝源性溃疡发生的重要原因。

The role of Helicobacter pylori infection with hepatogenic gastropathies

Objective To investigate the role of Helicobacter pylori （H.pylori） infection in patients with hepatogenic gastropathies.Methods 265 patients with chronic hepatitis B and 263 liver cirrhosis were studied. 158age-matched individuals with no evidence of hepatitis B virus （HBV） infection or liver diseases served as control. Serum samples from these groups were tested for using enzyme-linked immunosorbent assay （ELISA） and ^14C urea breath experiment（14C-UBT）. There were also used for rapid urease test.Results The prevalence of H.pylori in patients with hepatitis B, liver cirrhosis and control group were 48.3%,41.8% and 81.6% respectively. H.pylori infection was 48.1% in patients with hepatogenic ulcer,that was significantly lower than 90.6% in peptic ulcer of control patients （p 〈 0.005）. Conclusion The incidence of H.pyiori infection in hepatitis B virus-related liver disease was significantly lower than in non-chronic liver disease group. H.pylori infection might not be the main etiological factor for hepatogenic ulcer.