胺碘酮对持续性房颤患者P波离散度及血清hs-CRP的影响

目的探讨胺碘酮对持续性房颤患者P波离散度及血清超敏C反映蛋白（hs-CRP）的影响。方法 84例持续性房颤患者随机分为两组,观察组42例,对照组42例,对照组采用常规治疗,观察组在常规治疗的基础上加用胺碘酮治疗,两组共治疗8周。测定患者的P波离散度（Pd）和血清hs-CRP。结果观察组总有效率为95.2%,对照组总有效率为81%,两组比较有明显差异（P〈0.05）。两组治疗后均降低Pd和血清hs-CRP,并且与对照组比较,观察组降低更明显（P〈0.05）。结论采用胺碘酮可以降低持续性房颤患者的Pd和血清hs-CRP。

The effectiveness of Amiodarone on P wave dispersion and hs-CRP in patients with persistent atrial fibrillation

Objective To study the effectiveness of amiodarone on P wave dispersion and high-sensitivity C-reative protein（hs-CRP） in patients with persistent atrial fibrillation.Methods 84 patients with persistent atrial fibrillation were randomly divided into two groups,the control group（n=42 cases） and the observation group（n=42 cases）.The patients in the control group were treated by the conventional treatment,while the patients in the observation group were treated by the conventional treatment and amiodarone.They were all treated for eight weeks. P wave dispersion and hs-CRP were compared between two groups.Results The total efficicy rates were 95.2% in the observation group and 81% in the control group.There was a significant difference between two groups（P0.05）. P wave dispersion and hs-CRP were decreased after treatment in both groups. There was a significant difference between two groups（P0.05）.Conclusion Amiodarone can decrease P wave dispersion and hs-CRP in patients with persistent atrial fibrillation.