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恩度联合TP方案治疗中晚期非小细胞肺癌的临床观察
引用本文:徐丽叶,蒋葵,郑培实,张阳.恩度联合TP方案治疗中晚期非小细胞肺癌的临床观察[J].现代保健,2011(17):15-16.
作者姓名:徐丽叶  蒋葵  郑培实  张阳
作者单位:大连医科大学附属第二医院,116027
摘    要:目的评价恩度联合TP方案治疗中晚期非小细胞肺癌的临床疗效及安全性。方法选择中晚期非小细胞肺癌住院患者55例,随机分为对照组及观察组。两组均给予常规TP方案化疗,观察组另给予恩度治疗,两周期后评价疗效及毒副反应。结果观察组总有效率为57.1%,对照组总有效率为29.6%,治疗组总有效率高于对照组(P〈0.05)。两组问毒副反应发生率差异无统计学意义(P〉0.05)。结论恩度联合TP方案化疗治疗中晚期非小细胞肺癌是一种安全有效的方案,值得在临床上推广应用。

关 键 词:非小细胞肺癌  血管内皮抑素  恩度  联合治疗

Clincal observation of endu combinated TP plan on nonsmall - cell lung cancer
Authors:XU Li -ye  JIANG Kui  ZHENG Pei - shi  ZHANG Yang
Institution:. Second Affiliated Hospital of Dalian medical university, Dalian 116027, China
Abstract:Objective To eveluate the safety and curative effec of endu eombinated TP plan on nonsmall - cell lung caneer(NSCLC). Methods 55 eases of patients with metaphase and late NSCLC were selected and randomly divided into observation groups and control groups, all patients received chemotherapeuties with rip plan, pattients in observation groups received endu treatment in addition, after two groups, clinical curative effect and toxicity reaction was contrasted. Results Clinical effective power was 57.1% in observation groups and was 29.6% in control groups, clinical effective power was higher in observation groups than in control groups ( P 〈 0. 05 ). incidence rate of toxicity reaction was identical between observation groups and control groups ( P 〉 0, 05 ). Conclusion Endu combinated TP plan on nonsmall - cell lung cancer was safe and effective, was valuable for generalization application in clinic.
Keywords:Nonsmall - cell lung cancer  Recombinant human endostatin injection  Endu  Therapeutic alliance
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