Novel diffusion-weighted magnetic resonance imaging findings in leptomeningeal carcinomatosis: a case report |
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Authors: | Hu Y-F Chang F-C Hu H-H Hsu L-C |
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Affiliation: | a Departments of Internal Medicine and Radiology, and Neurological Institute, Taipei Veterans General Hospital, Taiwan, ROC; Departments of Radiology and Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC |
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Abstract: | This report presents a rare case of leptomeningeal carcinomatosis initially presenting with mental impairment and rapidly progressing to coma without any history of malignancy. In addition to highlighting the diagnostic difficulties, the linear high signal intensity along the cortex on the diffusion-weighted imaging (DWI) sequence of magnetic resonance (MR) imaging was identified accidentally. High signal change in the corresponding areas was also noted on unenhanced fluid-attenuated inversion recovery (FLAIR) MR imaging, which may be a novel method of diagnosing leptomeningeal carcinomatosis, which should be studied further. |
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Keywords: | Leptomeningeal carcinomatosis mental impairment MR imaging |
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