骨瓜提取物致过敏性休克36例文献分析 |
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引用本文: | 张明珠,何光照,曹烨君等.骨瓜提取物致过敏性休克36例文献分析[J].中国执业药师,2014(4):3-6. |
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作者姓名: | 张明珠 何光照 曹烨君等 |
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作者单位: | [1]常州市第四人民医院药剂科,江苏常州213032 [2]徐州医学院研究生学院,徐州221004 |
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基金项目: | 江苏省普通高校研究生科研创新计划项目(CXZZ11_0753) |
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摘 要: | 目的:探讨骨瓜提取物致过敏性休克的临床特点及发生规律,为临床合理用药提供参考。方法:以“骨瓜提取物”、“休克”、“过敏反应”为关键词进行检索,对文献中的有关数据进行统计与分析。结果:检索到骨瓜提取物致过敏性休克文献29篇,病例36例。骨瓜提取物在近两年引起过敏性休克25例,占69.4%,75.0%的过敏性休克发生在首次用药过程中,66.7%发生在用药开始后的10 min内。结论:骨瓜提取物注射剂导致过敏性休克发生时间短,病情危重,应引起临床高度重视。
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关 键 词: | 骨瓜提取物 过敏性休克 不良反应 合理用药 |
Literature Analysis of 36 Cases of Anaphylactic Shock Induced by Gugua Extractives |
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Authors: | Zhang Mingzhu He Guangzhao Cao Yejun He Lixia Deng Yuqin |
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Institution: | 1 Pharmacy Department of The Fourth People' s Hospital of Changzhou,Jiangsu Changzhou 213032,China;2 Graduate School of Xuzhou Medical College,Xuzhou 221004) |
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Abstract: | Objective:To investigate the clinical features and the regularity of anaphylactic shock induced by gugua extractives so as to provide a reference for rational drug use.Methods:To retrieve the case reports of anaphylactic shock induced by gugua extractives by key words searching and the data was analyzed statistically. Results:About 29 articles including 36 cases reported the anaphylactic shock caused by gugua extractives. About 25 cases (69.4%) of anaphylactic shock were caused by gugua extractives in the recent two years and 75.0%of anaphylactic shock occurred in the process of the first time using gugua extractives and 66.7% of the reactions happened within 10 minutes of the drug administration. Conclusion:The anaphylactic shock caused by gugua extractives usually occurred in a short time but with critical conditions. It should arouse more attention by clinicians. |
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Keywords: | Gugua Extractives Anaphylactic Shock Adverse Reaction Rational Drug Use |
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