| 代谢物组学在新药研究中的应用研究进展 |
| |
| 引用本文： | 赵立波 陈汇 曾繁典. 代谢物组学在新药研究中的应用研究进展[J]. 中国临床药理学杂志, 2006, 22(3): 224-226 |
| |
| 作者姓名： | 赵立波 陈汇 曾繁典 |
| |
| 作者单位： | 华中科技大学同济医学院临床药理研究所,湖北武汉430030 |
| |
| 摘 要： | 代谢物组学是近5年来发展起来的与基因组学、蛋白质组学等并列的学科。它运用核磁共振等分析技术，测定细胞和体液中内源性或外源性代谢物的经时变化，评价细胞功能和生物体的病理生理状态。本文综述其在新药开发中的作用。
|
| 关 键 词： | 代谢物组学 核磁共振 代谢物 |
| 文章编号： | 1001-6821（2006）02-0224-03 |
| 收稿时间： | 2004-10-25 |
| 修稿时间： | 2004-10-252005-12-06 |
Progress of metabonomics application in drugs reseach |
| |
| ZHAO Li -bo ,CHEN Hui, ZENG Fan - dian. Progress of metabonomics application in drugs reseach[J]. The Chinese Journal of Clinical Pharmacology, 2006, 22(3): 224-226 |
| |
| Authors: | ZHAO Li -bo CHEN Hui ZENG Fan - dian |
| |
| Affiliation: | Department of Pharmacology of Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China |
| |
| Abstract: | Metabonomics is a new " - omics" compared to genomics and proteomics, which developed in the last five years. NMR - based metabo-nomics describe the systemic response of organisms to physiological perturbations through time and get " fingerfrint". The applying of metabo-nomics involves in many aspect. In this paper, the use of metabonomics in drug research is reviewed. |
| |
| Keywords: | metabonomics nuclear magnetic spectroscopy metabolite |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
