牙菌斑中幽门螺杆菌与胃病的关系

目的 :分离培养口腔牙菌斑中的幽门螺杆菌 (Helicobackerpylori,Hp)并探讨它与Hp相关性慢性胃病之间的相互关系。方法 :采用细菌培养的方法检测 40例体检者的龈下牙菌斑和胃黏膜中的Hp。 结果 :10例 ( 2 7.0 3 % )慢性胃病患者的胃黏膜Hp培养阳性 ,其中 5例 ( 13 .5 1% )牙菌斑Hp培养阳性。 3例胃黏膜Hp培养阴性的非慢性胃病患者中有 1例牙菌斑Hp培养阳性。 结论 :牙菌斑是Hp的另一个重要储存库 ,口腔Hp的存在可能与慢性胃病有一定的相关性。

Relationship of Helicobacter pylori in dental plaque with gastric disease

Objectives: To inveatigate Helicobacter pylo r i (Hp) in dental plaque and its relevance to gastric disease.Methods: 40 physical examination subjects were recruited. Subgingival plaque and gastric biopsy samples were respectively collected for detection of Hpby in vitroculture. Results: Hpwas identified in gastric biopsy from ten of thirty-seven (27.03%) subjects with proven chronic gastric disease. From five of the ten, Hpwas isolated in their dental plaque. None of three subjects without chronic gastric disease had Hpin their gastric bi opsy. However, Hpwas found in dental plaque from one of the three.C onclusion: The results suggest that dental plaque is an ecological niche of Hp. Oral Hpmay be related to chronic gastric disease.