肠内和肠外营养支持对重型颅脑损伤预后的疗效观察

目的 观察早期肠内营养对重型颅脑损伤患者营养支持效果及预后.方法 将40例重型颅脑损伤患者随机分成肠内营养(EN组)和肠外营养(PN组),比较两组使用营养液前、使用后7 d、14 d上臂围(MAC)、上臂肌围(MAMC)、三头肌皮脂厚度(TSF)、血清白蛋白(ALB)、血红蛋白(Hb)代谢和预后情况.结果 EN组使用后7 d、14 d上臂围(MAC)、上臂肌围(MAMC)、血清白蛋白(ALB)、血红蛋白(Hb)检验指标高于PN组,EN组好转率80%、感染性并发症40%,PN组好转率70%、感染性并发症80%.结论 重型颅脑损伤患者早期肠内营养,有保护肠粘膜屏障、减少并发症,改善患者预后的作用.

Effects of enteral and parenteral nutrition therapy on severe craniocerebral injured patients

Objective To investigate the effects of early enteral nutrition (EN) and parenteral nutrition (PN) therapy on severe craniocerebral injured patients. Methods 40 patients with severe craniocerebral injury were randomly classified into EN group and PN group, and received EN and PN therapy, respectively. All patients in the two groups, the Midarm circumference (MAC), Midarm muscle circumference (MAMC), Triceps skinfold (TSF) and the levels of serum albumin (ALB) and hemoglobin (Hb) were measured before treatment and in day 7 and 14 after treatment, respectively. Results In day 7 and 14 after treatment, the MAC and MAMC in the EN patients were better than those in the PN patients. The levels of ALB and Hb were increased significantly in EN group compared with that in PN patients. The effective rate in EN and PN groups were 80% and 70%, respectively, while the complication rate in the two groups were 40% and 80% respectively. Conclusion Early enteral nutrition therapy may improve the nutritional situation and decrease complication in severe craniocerebral injured patients.