灵芝多糖口服液对老龄小鼠超氧化物歧化酶的影响

目的探讨灵芝多糖口服液对老龄小鼠的抗衰老作用。方法用Ｃ５７１２月～１８月老龄小鼠３６只，随机分为三组。Ａ组每只给灵芝多糖口服液０．３ｍｌ／１０ｇ；Ｂ组每只给灵芝多糖口服液０．１５ｍｌ／１０ｇ；Ｃ组每只给生理盐水０．２ｍｌ／１０ｇ，每天灌胃一次，１０天后，测定红细胞、肝细胞、脑细胞内的ＳＯＤ含量。结果Ａ组红细胞、脑细胞内ＳＯＤ含量与对照组相比明显增高（Ｐ＜０．０１），Ａ组肝细胞与Ｂ组红细胞、脑细胞、肝细胞内ＳＯＤ含量均增高（Ｐ＜０．０５）。结论灵芝多糖口服液可提高ＳＯＤ含量，增强机体对自由基的清除能力，故能减少自由基对机体的损伤，有延缓衰老之功效。

EFFECT OF GANODERMA POLYSACCHARIDE ON SUPEROXIDE DISMUTASE OF OLD-MICE

Objective:To study the anti-aging effect of ganoderma polysaccharide on old-aged mice.Method:Thirty-six old-aged mice C57 between 12-18 months were divided into three groups (AB and C)randomly and were administered by transgastric perfusion 0.3ml/10g and 0.15ml/10g of ganoderma polysaccharide solution and 0.2 ml/10g of normal saline respectively.Ten days later,the contents of SOD in erythrocyte ,hepatocyte and cerebral cell were detected respectively.Results:The contents of SOD in erythrocyte and cerebral cell in group A were remarkably higher than those in group c (P<0.01).The contents of SOD in erythrocyte,cerebral cell of group B and in hepatocyte of both group A and group B were higher than those in group C(P<0.05).Conclusion:Ganoderma polysaccharide solution can increase the content of SOD and improve body's capacity of clearing free radical,which reduce damages of free radical to organism and produce anti-aging effects.