| 唇唾液腺和泪腺活检诊断Sjogren综合征 |
| |
| 引用本文： | 徐克萍,坪田一男.唇唾液腺和泪腺活检诊断Sjogren综合征[J].中华眼科杂志,1997,33(3):222-225. |
| |
| 作者姓名： | 徐克萍 坪田一男 |
| |
| 作者单位： | 上海市第一人民医院眼科(徐克萍)，日本东京齿科大学眼科(坪田一男) |
| |
| 基金项目： | 日本东京上原纪念生命科学奖学金资助 |
| |
| 摘 要： | 目的探讨唇唾液腺和泪腺活检组织的局灶性腺炎在诊断Ｓｊｏｇｒｅｎ综合征的价值。方法对１０５例可疑Ｓｊｏｇｒｅｎ综合征患者进行活检。Ｓｊｏｇｒｅｎ综合征的诊断按照Ｆｏｘ标准，活检诊断按照Ｃｈｉｓｈｏｌｍ－Ｍａｓｏｎ分级和Ｇｒｅｅｎｓｐａｎ分灶标准。结果肌上皮岛和重度淋巴细胞浸润伴生发中心仅出现在泪腺活检组织中。采用双重组织诊断Ｓｊｏｇｒｅｎ综合征较采用单一组织诊断明显有效。结论对可疑Ｓｊｏｇｒｅｎ综合征患者同时行唇唾液腺和泪腺活检可增加诊断的正确性
|
| 关 键 词： | 唇 泪器 综合征 细胞诊断 |
Biopsy of labial salivary glands and lacrimal glands in the diagnosis of Sj?gren's syndrome] |
| |
| K Xu,T Kazuo.Biopsy of labial salivary glands and lacrimal glands in the diagnosis of Sj?gren''s syndrome][J].Chinese Journal of Ophthalmology,1997,33(3):222-225. |
| |
| Authors: | K Xu T Kazuo |
| |
| Institution: | Department of Ophthalmology, Shanghai First People's Hospital. |
| |
| Abstract: | OBJECTIVES: To determine the diagnostic value for Sj?gren's syndrome (SS) by evaluating the presence of focal adenitis in labial salivary gland (LSG) and lacrimal gland (LG) biopsy specimens. METHODS: 109 suspected cases with SS underwent the biopsies. The diagnostic criteria of Fox et al. were followed. Both Chisholm-Manson's grading standard and Greenspan's focus score were used for the evaluation. RESULTS: Myoepithelial islands and severe lymphocyte infiltration with germinal centers were observed only in LG biopsy specimens. The lymphocytic foci scored of LG were significantly higher than that of LSG in 23 cases having both biopsy results. The evaluation of both kinds of specimen for such a patient was significantly more effective in diagnosing SS than using either one of them alone. CONCLUSION: We recommend that both LSG and LG biopsies be performed in patients suspected of having SS to reduce false negative results and improve diagnostic accuracy. |
| |
| Keywords: | Lip Lacrimal apparatus Syndrome Cytodiagnosis |
| 本文献已被 CNKI 维普 等数据库收录！ |
