干眼患者睑板腺状况的分析

目的 探讨临床诊断为干眼症患者的睑板腺状态。方法 非干预性、观察性研究。2010年3至12月在北京大学第三医院眼科诊断为干眼的194例（388只眼）作为研究对象。其中男性69例（138只眼）,女性125例(250只眼),总体年龄范围7～ 85岁,平均年龄（44±18）岁,男性平均年龄(39±18)岁,女性平均年龄(47±17)岁。检查指标包括主观症状评分、泪液分泌试验、泪膜破裂时间(BUT)及角膜荧光染色情况,同时利用非接触红外线睑板腺照相系统进行睑板腺检查。结果 观察的194例（388只眼）主观症状平均(5.47±2.14)分,SIaT值为(5.58±4.22) mm,BUT为(3.09±2.34)s,角膜荧光素染色评分(4.10±3.79)分。睑板腺照相评分为1分占3.09％（12只眼）,2分占9.28％（36只眼）,3分占20.10％（78只眼）,4分占26.03％（101只眼）,5分占21.91％（85只眼）,6分占19.59％（76只眼）。结论 睑板腺功能障碍是干眼症的重要病因之一。非接触红外线睑板腺照相系统可以客观评价睑板腺形态。

Analysis of the meibomian glands condition in dry eye patients

Objective To evaluate the condition of meibomian glands in dry eye patients. Methods Noninterventional, observational study. 388 eyes from 194 patients which were diagnosed as dry eye during March to December 2010 were collected, 69 males ( 138 eyes), 125 females (250 eyes). Patients' age range 7-85 years, mean(44 ± 18)years. Symptom score, Schirmer test I a (S I aT), tear film break-up time (BUT) and superficial punctuated keratopathy were measured. The meibomian glands were observed using the noncontact meibngraphy system. ResultsIn all subjects, symptom score 5.47 ± 2. 14, S I aT (5.58 + 4. 22) mm, BUT ( 3.09 ± 2. 34 ) s, superficial punctuated keratopathy score 4. 10 + 3.79. Meiboscore:l point, 3.09％ ( 12 eyes) ;2 points, 9. 28％ (36 eyes) ;3 points, 20. 10％ (78 eyes) ;4 points,26.03％(101 eyes);5 points, 21.91％(85 eyes);6 points,19.59％ (76 eyes). Conclusions Abnormal meibomian glands occupied a extremely high proportion of dry eye which indicate that meibomian glands disorder plays important role in dry eye. Noncontact meibography system could show accurate structure of meibomian glands.