支气管内超声引导针吸活检术在肺癌分期的应用

目的 接受EBUS-TBNA检查,其评价支气管内超声引导针吸活检术(endobronchial ultrasound-guided transbronchial needle aspiration,EBUS-TBNA)在肺癌分期的应用价值.方法 2008年7月至2010年3月,128例肺癌患者中男102例,女26例,年龄37 -85岁,平均60.1岁.胸部CT或PET/CT影像学检查均提示肺癌并肺门或纵隔淋巴结肿大,未除外转移.回顾分析其临床影像学与内镜超声的表现及穿刺活检的结果.结果 128例内镜超声均可见肺门或纵隔多组肿大的淋巴结,短径6～16 mm,平均12.3 mm.成功穿刺189组淋巴结,过程顺利,无并发症发生.EBUS-TBNA准确率98.53％,灵敏度98.50％,特异度100％.结论EBUS-TBNA作为肺门及纵隔淋巴结活检的一种新手段,创伤小,并发症少,准确性高,在肺癌分期的应用安全、可行.

Endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) for staging of lung cancer

Objective To evaluate the clinical effects of endobronchial ultrasound - transbronchial needle aspiration (EBUS-TBNA) in the evaluation of staging of lung cancer.Methods Between July 2008 to March 2010,the first 128 patients selected by CT or PET/CT scanning with lung cancer in whom metastatic carcinoma in the hilar and/or mediastinal lymph nodes underwent EBUS-TBNA and were clinically followed up.There were 102 males and 26 femals with the age of 37 - 85 years,average 60.1 years.Review the performance in check and the result of biopsy.Results From 128 patients of mean age 60.1 years ( range 37 - 85 ),189 lymph nodes were punctured.The mean diameter of the nodes was 12.3 mm and the range was 6-16 mm.There were no procedural complications.Accuracy,sensitivity,and specificity for EBUS-TBNA were 98.53％,98.50％,and 100％,respectively.Conclusion EBUS-TBNA allows real-time visualization of mediastinal and hilar lymph nodes,allowing sampling safely and efficiently.It has great potential for diagnosis of staging of lung cancer.