单次插管剂量维库溴铵残余肌松与术中低温的关系

目的 研究单次插管剂量维库溴铵的术后残余肌松的发生率及其与术中低温的关系.方法 民航医学中心(民航总医院)麻醉科2009年7至12月80例只用单次插管剂量维库溴铵的全麻患者,其中男36例,女44例,年龄19 ～59岁.常规麻醉诱导维持,术中无肌松剂追加.术中鼻咽体温(T)＜36℃为术中低温组(LBT组)否则为非术中低温组(NBT组).术毕在麻醉后恢复室(PACU)根据临床拔管指征拔除气管插管,拔管后即刻测定4个成串刺激比值(TOFr).结果 单次插管剂量维库溴铵残余肌松发生率为28.7％.LBT组37例患者中,有16例患者发生术后残余肌松,术后残余肌松发生率为43.2％.NBT组43例患者中,有7例患者发生术后残余肌松,术后残余肌松发生率为16.3％.LBT组与NBT组相比术后残余肌松发生率差异有统计学意义P＜0.05.结论 术中低温术后肌松残余的发生率增高.

The relationship between the intraoperative hypothermia and the residual neuromuscular of single intubation dose of vecuronium

Objective To study the relationship between the intraoperative hypothermia and the residual neuromuscular of single intubation dose of vecuronium.Methods The designed patients were from July to December in 2009.There are 36 male and 44 female cases.Their age was 19 to 59 years.The induction and sustaining are routine method.There were no additional muscle relaxant.Intraoperative nasopharyngeal temperature ( T ) ＜ 36 ℃ for the intraoperative hypothermia ( LBT group ) or nonintraoperative hypothermia group (NBT group ).The patients turn back the PACU with tracheal intubation.Measured TOFr immediately after extubation.Results The incidence of residual neuromuscular single intubation dose of vecuronium was 28.7％.The incidence of postoperative residual neuromuscular was 43.2％ ( 16/37 ) in the LBT group.The incidence of postoperative residual neuromuscular was 16.3％ (7/43) in the NBT group.LBT group compared with the NBT group the incidence of postoperative residual neuromuscular was significant differences( P ＜ 0.05 ).Conclusion The incidence of residual neuromuscular increases.When patients in the surgery exist low body temperature.