| 变应性鼻炎鼻分泌物中上皮细胞集落和嗜酸粒细胞的检测 |
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| 引用本文： | 杨平常,范道生,张涛源,王长生.变应性鼻炎鼻分泌物中上皮细胞集落和嗜酸粒细胞的检测[J].中华耳鼻咽喉头颈外科杂志,1996(3). |
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| 作者姓名： | 杨平常 范道生 张涛源 王长生 |
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| 作者单位： | 山西医学院第一附属医院耳鼻咽喉科!太原，030001，山西医学院第一附属医院耳鼻咽喉科!太原，030001，山西医学院第一附属医院耳鼻咽喉科!太原，030001，山西医学院第一附属医院耳鼻咽喉科!太原，030001 |
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| 摘 要： | 为了观察变应性鼻炎（allesgicrhinitis，AR）患者鼻分泌物中的上皮细胞集落和嗜酸粒细胞，对20例AR患者（AR组）和15例鼻窦炎患者（感染组）鼻分泌物中细胞成分进行了电镜观察，发现AR组鼻分泌物中有大量上皮细胞集落，其特征是数个至数十个上皮细胞成片状脱落，上皮细胞集落的数量和嗜酸粒细胞的数量、嗜酸粒细胞阳离子蛋白（eosinophiliccationicprotein，ECP）的含量呈正相关。感染组中上皮细胞集落和嗜酸粒细胞极少，ECP含量甚微。结果提示嗜酸粒细胞的ECP可能导致AR患者的鼻粘膜上皮呈片状脱落，对上皮结构造成损害。
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| 关 键 词： | 鼻炎.变应性.常年 嗜酸细胞 上皮细胞 |
Cluster epithelial cells in nasal secretions of allergic rhinitis and its relation to eosinophils |
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| Yang Pingchang, Fan Daosheng, Zhang Taoyuan,et al..Cluster epithelial cells in nasal secretions of allergic rhinitis and its relation to eosinophils[J].Chinese JOurnal of Otorhinolaryngology Head and Neck Surgery,1996(3). |
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| Authors: | Yang Pingchang Fan Daosheng Zhang Taoyuan |
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| Institution: | Yang Pingchang, Fan Daosheng, Zhang Taoyuan, et al. First Affiliated Hospital,Shanxi Medical Col-lege,Taiyuan 030001 |
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| Abstract: | The cytology of nasal secretions in 20 patients with allergic rhinitis and 15 patients with chronic maxillary sinusitis was investigated with transmission electron microscope to study the ultrastructure of the cluster epithelial cells in nasal secretions of allergic rhinitis. The results showed that .the cluster epithelial cells were predominant cellular element in allergic nasal secretions. The number of cluster cells correlated positively with the number of eosinophils and the levels of eosinophilic cationic protein. It is suggested that the exfoliation of cluster nasal epithelial cellular ele-ments may be caused by eosinophic cationic protein with resultant hyperreactivity of nasal mucosa. |
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| Keywords: | Rhinitis allergic perennial Eosinophils Epithelial cells |
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