| 原发性肺非霍奇金淋巴瘤的临床特点及预后分析 |
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| 引用本文： | 李剑,焦力,张薇,段明辉,邹农,周道斌,沈悌.原发性肺非霍奇金淋巴瘤的临床特点及预后分析[J].基础医学与临床,2011,31(5). |
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| 作者姓名： | 李剑 焦力 张薇 段明辉 邹农 周道斌 沈悌 |
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| 作者单位： | 中国医学科学院,北京协和医学院,北京协和医院,血液内科,北京,100730 |
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| 摘 要： | 目的研究原发性肺非霍奇金淋巴瘤(PPL)的临床特征及预后。方法回顾性分析北京协和医院确诊的30例PPL的临床表现、诊断手段、病理类型以及预后。结果病例中,男性占46.7%,中位年龄为46岁。PPL患者没有特异的临床症状及影像学表现,甚至20%患者可无任何症状。中位发病至诊断时间为8个月,经支气管肺活检及经CT引导下肺活检的诊断率分别为33.3%和50%,而胸腔镜下肺活检及开胸肺活检的诊断率为100%。黏膜相关淋巴组织(MALT)淋巴瘤最为常见,占56.7%。在中位随诊39个月后,30例患者中有7例患者(23.3%)死亡。MALT组患者较非MALT组患者有着更低的IPI评分及更好的预后。结论 PPL是一种罕见的结外淋巴瘤,其诊断较为困难,非MALT类型的淋巴瘤患者预后较差。
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| 关 键 词： | 非霍奇金淋巴瘤 肺 原发性 临床特征 |
Clinical characteristics and prognosis of primary pulmonary non-Hodgkin's lymphoma |
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| LI Jian,JIAO Li,ZHANG Wei,DUAN Ming-hui,ZOU Nong,ZHOU Dao-bin,SHEN Ti.Clinical characteristics and prognosis of primary pulmonary non-Hodgkin's lymphoma[J].Basic Medical Sciences and Clinics,2011,31(5). |
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| Authors: | LI Jian JIAO Li ZHANG Wei DUAN Ming-hui ZOU Nong ZHOU Dao-bin SHEN Ti |
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| Institution: | LI Jian,JIAO Li,ZHANG Wei,DUAN Ming-hui,ZOU Nong,ZHOU Dao-bin,SHEN Ti(Dept.of Hematology,PUMC Hospital,CAMS & PUMC,Beijing 100730,China) |
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| Abstract: | Objective To study the clinical characteristics and outcome of patients with primary pulmonary non-Hodgkin's lymphoma(PPL).Methods The clinical features,diagnostic methods,pathological types and outcome of 30 patients with PPL diagnosed in PUMC Hospital were analyzed retrospectively.Results Of these 30 patients,46.7% of patients were male and the median age was 46 years.These patients didn't have specific clinical symptoms and radiological features and 20% patients were asymptomatic.The median time from ons... |
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| Keywords: | non-Hodgkin's lymphoma lung primary clinical characteristics |
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