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针刺镇痛在分娩中的作用及其机制
引用本文:朱庆双,王凤英,孙晓燕. 针刺镇痛在分娩中的作用及其机制[J]. 基础医学与临床, 2011, 31(6)
作者姓名:朱庆双  王凤英  孙晓燕
作者单位:首都医科大学,宣武医院妇产科,北京,100053
基金项目:北京市中医药科技项目(JJ2006-27)
摘    要:目的观察针刺对分娩镇痛的临床效果及作用机制,寻找一种安全有效、简便可行的分娩镇痛方法。方法随机抽样法选择针刺组16例、针刺+电刺激组29例和对照组46例,以视觉模拟评分疼痛分级法(VRS)评定镇痛效果,记录产程进展及产后出血情况、新生儿Apgar评分及体质量,观察针刺对母婴的影响。用高效液相色谱法(HPLC)检测针刺前后外周血中去甲肾上腺素(NA)及β-内啡肽(β-EP)含量变化,探讨该方法的镇痛机制。结果针刺镇痛后VAS评分下降,疼痛缓解率82.76%,明显高于对照组的17.94%,并明显提高外周血中β-EP浓度,针刺后血β-EP及NA分别为(5.20±0.93)mg/L及(1 230±18)ng/L,显著高于对照组的(4.38±0.67)mg/L及(783±31)ng/L(P<0.05)。结论针刺能有效减轻第一产程分娩疼痛,其镇痛效果可能是通过针刺使脑内具有镇痛作用的递质β-EP含量明显增加有关。

关 键 词:针刺镇痛  分娩  产程  

Acupuncture analgesia in childbirth,the efficacy and mechanism
ZHU Qing-shuang,WANG Feng-ying,SUN Xiao-yan. Acupuncture analgesia in childbirth,the efficacy and mechanism[J]. Basic Medical Sciences and Clinics, 2011, 31(6)
Authors:ZHU Qing-shuang  WANG Feng-ying  SUN Xiao-yan
Affiliation:ZHU Qing-shuang,WANG Feng-ying,SUN Xiao-yan(Dept.Obstetrics and Gynecology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)
Abstract:Objective To observe labor analgesia acupuncture's mechanism and efficacy for development of a safe and effective labor analgesia.Methods The acupuncture group 16 cases,the acupuncture + electricity stimulation group 29 cases and the control group 46 cases,(VRS ache staging) were organized to evaluate the analgesic effect by the visual simulation grading law,the record course of childbirth progress and the postpartum hemorrhage situation,the newborn Apgar grading and the newborn body mass for observation of...
Keywords:acupuncture analgesia  childbirth  labor  
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