Smoking,the oral contraceptive pill,and Crohn's disease |
| |
| Authors: | Dr. A. J. Wakefield FRCS A. M. Sawyerr MRCP M. Hudson MRCP A. P. Dhillon FRCP R. E. Pounder FRCP |
| |
| Affiliation: | (1) Inflammatory Bowel Disease Study Group, Academic Department of Medicine, Royal Free Hospital School of Medicine, Pond Street, NW3 2QG London, England;(2) Academic Department of Histopathology, Royal Free Hospital School of Medicine, Pond Street, NW3 2QG London, England |
| |
| Abstract: | Both cigarette smoking and the oral contraceptive pill have been implicated as aggravating factors in Crohn's disease. Based upon the recent demonstration of multifocal gastrointestinal infarction in Crohn's disease, a possible pathogenic mechanism for this condition, we propose how smoking and the oral contraceptive pill may potentiate a tendency for focal thrombosis and hence exacerbate the activity of Crohn's disease. |
| |
| Keywords: | Crohn's disease procoagulant activity smoking oral contraceptive |
| 本文献已被 SpringerLink 等数据库收录！ |
|
