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| 番茄红素对大鼠肺氧化损伤的影响 | |
| 引用本文： | 潘洪志,万丽葵,孙胜波,那立欣,李省三,曹军. 番茄红素对大鼠肺氧化损伤的影响[J]. 卫生研究, 2004, 33(5): 589-590 |
| 作者姓名： | 潘洪志 万丽葵 孙胜波 那立欣 李省三 曹军 |
| 作者单位： | 1. 哈尔滨医科大学公共卫生学院,哈尔滨,150001 2. 黑龙江省疾病预防控制中心 3. 黑龙江出入境检验检疫局 4. 齐齐哈尔医学院 |
| 摘 要： | 目的 观察臭氧对大鼠造成的氧化损伤和番茄红素 (LP)对损伤的影响。方法 利用臭氧吸入造成氧化损伤模型 ,以黄嘌呤氧化酶法测定血清和肺匀浆的SOD活性 ,硫代巴比妥显色法测定MDA含量 ,DTNB比色法测定GSH Px活力。结果 各番茄红素给药组的大鼠血清和肺组织的SOD活性、GSH Px活力上升 ,MDA含量降低 ,与模型组相比差异有显著性 (P <0 0 5 )。结论 番茄红素可以保护臭氧造成的大鼠氧化损伤 |
| 关 键 词： | 番茄红素 臭氧 氧化损伤 保护 |
| 文章编号： | 1000-8020(2004)05-0589-02 |
| 修稿时间： | 2004-02-10 |
Protective effect of lycopene on the oxidative damage of lung in rat induced by ozone |
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| Pan Hongzhi,Wan Likui,Sun Shengbo,Na Lixin,et al.. Protective effect of lycopene on the oxidative damage of lung in rat induced by ozone[J]. Journal of hygiene research, 2004, 33(5): 589-590 | |
| Authors: | Pan Hongzhi Wan Likui Sun Shengbo Na Lixin et al. |
| Affiliation: | School of Public Health, Harbin Medical University, Harbin 150001, China. |
| Abstract: | Objective To observe the effect of Lycopene(LP) on the oxidative damage of lung induced by exposing ozone. Methods The injury model of lung was induced by exposing ozone. The xanthines oxidize method and TBA was used to determine SOD, MDA and GSH-Px in serum and lung respectively. Results Compared with model rats,SOD and GSH-Px in the group of LP administrated were increased and MDA were decreased significantly(P<0.05). Conclusion it was showed that LP could protect oxidative damage of lung induced by ozone in rats. |
| Keywords: | lycopene ozone oxidative damage protection |
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