Effects of milnacipran on binge eating - a pilot study |
| |
Authors: | Noma Shun'ichi Uwatoko Teruhisa Yamamoto Haruka Hayashi Takuji |
| |
Institution: | Department of Psychiatry, Graduate School of Medicine, Kyoto University Kyoto, Japan. |
| |
Abstract: | Selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors are effective in the treatment of bulimia nervosa. There have been relatively few studies of the efficacy of specific serotonin and norepinephrine reuptake inhibitors in the treatment of eating disorders. Twenty-five outpatients with binge eating episodes, diagnosed as anorexia nervosa, binge-eating/purging type, bulimia nervosa/purging type, or bulimia nervosa/non-purging type, were treated with milnacipran and 20 patients completed the 8-week study. Symptom severity was evaluated using the Bulimic Investigatory Test, Edinburgh (BITE) self-rating scale before administration of milnacipran and after 1, 4, and 8 weeks treatment. The scores improved after 8 weeks, especially drive to, and regret for, binge eating. Milnacipran was more effective in patients without purging and in younger patients, while there was no difference in the efficacy of milnacipran among subtypes of eating disorders. |
| |
Keywords: | milnacipran specific serotonin and norepinephrine reuptake inhibitors binge eating vomiting eating disorder pharmacotherapy |
本文献已被 PubMed 等数据库收录! |
|