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OSAHS合并2型糖尿病行改良悬雍垂腭咽成形术后对血糖影响的临床观察
引用本文:刘竺,张洪,张正健,张茜蕾,魏云,李森,沈亮.OSAHS合并2型糖尿病行改良悬雍垂腭咽成形术后对血糖影响的临床观察[J].临床和实验医学杂志,2011,10(7):501-503.
作者姓名:刘竺  张洪  张正健  张茜蕾  魏云  李森  沈亮
作者单位:达州市第二人民医院耳鼻咽喉头颈外科,四川,达州,635000
摘    要:目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并Ⅱ型糖尿病行改良悬雍垂腭咽成形术(H-UPPP)治疗对血糖的影响。方法经多导睡眠监测(PSG)检查确诊为OSAHS同时合并经内分泌专科确诊为2型糖尿病的患者18例,分别常规采静脉血测手术前空腹血糖12.30±2.50 mmol/L,餐后2 h血糖19.50±3.10 mmol/L、手术后7 d空腹血糖11.20±1.60 mmol/L,餐后2 h血糖15.70±2.40 mmol/L及手术后180 d空腹血糖6.28±0.40 mmol/L,餐后2 h血糖7.65±0.12 mmol/L进行对比分析。结果手术前与手术后7 d空腹和餐后2 h血糖各指标差异无统计学意义(P>0.05),手术前、手术后7 d与手术后180 d空腹和餐后2 h血糖各指标差异有统计学意义(P<0.05)。结论 OSAHS可以成为Ⅱ型糖尿病的病因。OSAHS通过H-UPPP治疗可以改善缺氧,提高机体对胰岛素的敏感性,从而有效控制2型糖尿病的血糖。

关 键 词:睡眠呼吸暂停低通气综合征  阻塞性2型糖尿病  血糖  改良悬雍垂腭咽成形术

Clinical observation of the effect of modified uvulopalatopharyngoplasty on blood sugar in OSAHS patients complicated with type 2 diabetes mellitus
LIU Zhu,ZHANG Hong,ZHANG Zheng-Jian,et al..Clinical observation of the effect of modified uvulopalatopharyngoplasty on blood sugar in OSAHS patients complicated with type 2 diabetes mellitus[J].Journal of Clinical and Experimental Medicine,2011,10(7):501-503.
Authors:LIU Zhu  ZHANG Hong  ZHANG Zheng-Jian  
Institution:LIU Zhu,ZHANG Hong,ZHANG Zheng-Jian,et al.The Department of Otorhinolaryngology and Head-Neck Surgery,The Second People's Hospital of Dazhou,Dazhou,Sichuan 635000,China
Abstract:Objective To explore the effect of modified uvulopalatopharyngoplasty(H-UPPP) on blood sugar in patients with obstructive sleep apnea-hypopnea syndrome(OSAHS) and type 2 diabetes mellitus(T2DM).Methods Eighteen OSAHS patients complicated with T2DM participated in this study.OSAHS was confirmed by polysomography(PSG) examination.The diagnosis of T2DM was made by endocrinological examinations.Fasting blood sugar and 2 h postprandial blood glucose were detected before and 7 d and 180 d after H-UPPP.The results...
Keywords:OSAHS  Type 2 diabetes mellitus  Blood Sugar  H-UPPP  
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