| 可吸收型羟基磷灰石生物陶瓷的临床应用评估 |
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| 引用本文： | 何文丹,陈建钢,帅李娅.可吸收型羟基磷灰石生物陶瓷的临床应用评估[J].临床口腔医学杂志,2011,27(3):171-174. |
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| 作者姓名： | 何文丹 陈建钢 帅李娅 |
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| 作者单位： | 武汉大学中南医院口腔科,湖北,武汉,430071 |
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| 摘 要： | 目的：观察可吸收型羟基磷灰石生物陶瓷临床应用中的疗效和安全性,旨在为临床提供一种新型植骨材料。方法：60例口腔骨缺损患者分为两组：实验组植入可吸收型羟基磷灰石生物陶瓷,对照组植入牛无机骨Bio-Oss颗粒。通过术前术后对体温、血常规、血沉（ESR）、C-反应蛋白（CRP）、肝肾功能（ALT、AST、Bun、Cr）,以及伤口愈合、骨愈合情况等指标的监测,对实验用植骨材料进行临床评价。结果：实验组植入材料后6个月,无1例全身性异常反应,仅1例伤口有红肿,渗液,3周内伤口愈合。骨愈合情况：植入区的骨密度增高,骨愈合良好,实验组与对照组无明显差异。结论：可吸收型羟基磷灰石可用于拔牙创及牙种植周围骨缺损修复,该材料无不良反应,无毒副作用,能加速骨缺损的修复。
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| 关 键 词： | 骨缺损 可吸收型羟基磷灰石 疗效性 安全性 |
A clinical assessment on biodegradable coral-hydroxyapatite ceramic |
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| HE Wen-dan,CHEN Jian-gang,SUAI Li-ya.A clinical assessment on biodegradable coral-hydroxyapatite ceramic[J].Journal of Clinical Stomatology,2011,27(3):171-174. |
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| Authors: | HE Wen-dan CHEN Jian-gang SUAI Li-ya |
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| Institution: | HE Wen-dan,CHEN Jian-gang,SUAI Li-ya.Department of Stomatology,Zhongnan Hospital,Wuhan University,Hubei Wuhan 430071,China. |
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| Abstract: | Objective:To investigate the efficacy and safety of the Biodegradable Coral-hydroxyapatite Ceramic (BCHA) in clinical application.Method:60 cases of Oral bone defects were divided into 2 groups,BCHA and inorganic bovine bone Bio-Oss particles were applied to the A(experimental group) and B group(control group).By compared with preoperative and postoperative changes of body temperature,blood count,erythrocyte sedimentation rate (ESR),C-reactive protein(CRP),liver and kidney function(ALT,AST,Bun,Cr),and wound... |
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| Keywords: | bone defect biodegradable coral-hydroxyapatite efficacy safety |
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