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丙戊酸钠对精神分裂症攻击行为的辅助治疗作用
引用本文:景艳玲,王东明,孙祥虹,曲春晖.丙戊酸钠对精神分裂症攻击行为的辅助治疗作用[J].临床精神医学杂志,2011,21(1):58-60.
作者姓名:景艳玲  王东明  孙祥虹  曲春晖
作者单位:山东青岛市精神卫生中心,266034
摘    要:目的:观察丙戊酸钠合用利培酮治疗精神分裂症攻击行为的疗效与不良反应。方法:63例伴有攻击行为的精神分裂症住院患者分为丙戊酸钠合用利培酮组(研究组)32例和单用利培酮组(对照组)31例,治疗12周。应用阳性和阴性症状量表(PANSS)及治疗中出现的症状量表(TESS)评定疗效及不良反应。结果:研究组PANSS评分(包括兴奋症状分及攻击因子分)改善明显优于对照组(P〈0.05)。研究组较对照组不良反应少且程度轻(P〈0.05)。结论:丙戊酸钠合并利培酮治疗精神分裂症攻击行为的疗效肯定,安全性与耐受性较好。

关 键 词:丙戊酸钠  利培酮  精神分裂症

A comparative study of valproate with risperidone in the treatment of schizophrenia with aggressive behavior
JING Yan-ling,WANG Dong-ming,SUN Xiang-hong,QU Chun-hui.A comparative study of valproate with risperidone in the treatment of schizophrenia with aggressive behavior[J].Journal of Clinical Psychological Medicine,2011,21(1):58-60.
Authors:JING Yan-ling  WANG Dong-ming  SUN Xiang-hong  QU Chun-hui
Institution:JING Yan-ling,WANG Dong-ming,SUN Xiang-hong,QU Chun-hui.Qingdao Mental Health Center,Shandong Province,Qingdao 266034,China
Abstract:Objective: To study the efficacy and safety of valproate combined with risperidone in the treatment of schizophrenia with aggressive behavior. Method:A total of 63 schizophrenic inpatients with aggression were divided into two groups,32 cases were treated with valproate combined with risperidone (study group) and 31 cases were treated with risperidone (control group) for 12 weeks.Positive and negative syndrome scale (PANSS),and treatment emergent symptom scale (TESS) were used to assess the efficacy and saf...
Keywords:valproate  risperidone  schizophrenia  
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