Oral manifestation in inflammatory bowel disease:A review |
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Authors: | Kamran B Lankarani ;Gholam Reza Sivandzadeh ;Shima Hassanpour |
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Institution: | [1]Department of Internal Medicine, Healthcare Policy Research Center, Shiraz University of Medical Sciences; [2]Department of Internal Medicine, Gastroenterohepatology Research Center, Namazi Hospital, Shiraz University of Medical Sciences; [3]Gastroenterohepatology Research Center, Namazi Hospital, Shiraz University of Medical Sciences |
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Abstract: | Inflammatory bowel diseases (IBDs), including Crohn’s disease (CD) and ulcerative colitis, not only affect the intestinal tract but also have an extraintestinal involvement within the oral cavity. These oral manifestations may assist in the diagnosis and the monitoring of disease activity, whilst ignoring them may lead to an inaccurate diagnosis and useless and expensive workups. Indurated tag-like lesions, cobblestoning, and mucogingivitis are the most common specific oral findings encountered in CD cases. Aphthous stomatitis and pyostomatitis vegetans are among non-specific oral manifestations of IBD. In differential diagnosis, side effects of drugs, infections, nutritional deficiencies, and other inflammatory conditions should also be considered. Treatment usually involves managing the underlying intestinal disease. In severe cases with local symptoms, topical and/or systemic steroids and immunosuppressive drugs might be used. |
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Keywords: | Inflammatory bowel disease Crohn’s disease Ulcerative colitis Extra-intestinal manifestations Pyostomatitis vegetans Aphthous stomatitis Cobblestoning Mucogingivitis Oral manifestation |
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