沈阳市城区2000-2009年女性乳腺癌发病趋势分析

目的探讨2000～2009年沈阳市城区女性乳腺癌发病率、年龄分布及变化趋势。方法收集2000～2009年沈阳市疾控中心肿瘤登记报告系统登记的女性乳腺癌发病资料，采用SPSS16．0软件对乳腺癌发病率、标化发病率进行分析。发病趋势采用r趋势检验和线性回归分析。结果2000～2009年沈阳市城区女性乳腺癌年均粗发病率46．03／10万，年均标化发病率35．63／10万，10年间上升了160．41％和109．39％，平均每年递增11．22％和8．56％。粗发病率和标化发病率均呈上升趋势，差异有统计学意义（P〈0．001）。50。64岁年龄组发病率呈直线上升趋势，10年上升271．97％，平均每年递增15．72％。经矿趋势检验及线性回归分析，差异均有统计学意义（x^2=276．743，P=O．000；y=-22355．560＋11．205x，P=0．000）。结论沈阳市城区女性乳腺癌发病率呈上升趋势，并且有发病低龄化，50～64岁年龄组较多发的特点。

Incidence Trend of Female Breast Cancer in Urban Shenyang from 2000 to 2009

Objective To explore the incidence, age distribution and change tendency of female breast cancer in urban Shenyang from 2000 to 2009. Methods The incidence data of female breast cancer recorded in Shenyang Center for Disease Control and Prevention from 2000 to 2009 were collected, and the incidence and standardized incidence of breast cancer were analyzed by using SPSS 16.0 software. The incidence trend was analyzed by means of X2 trend test and linear regression. Results The annual average crude incidence rate of female breast cancer in urban Shenyang from 2000 to 2009 was 46.03/100 000, while the annual average standardized incidence rate was 35.63/100 000, increased by 160.41% and 109.39% respectively during past 10 years, and the annual average increase was 11.22% and 8.56%, respectively. Both crude incidence rate and standardized incidence rate were in increasing trends with statistical significance （P〈0.001）. The crude incidence rate of the female at age of 50-64 showed a perpendicular rise trend, increased by 271.97%, and the annual average increase was 15.72%. The X2 trend test and linear regression showed a significant difference （X2=276.743, P=0.000; y= -22 355.560＋ 11.205x, P=0.000）. Conclusion The incidence of female breast cancer in urban Shenyang tends to rise with a vounger-a~ed trend, and the female at a~e of 50-64 are commonly affected