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子宫颈鳞癌雌、孕激素受体表达及其与淋巴结转移的关系研究
引用本文:古丽娜,陈晓,拉莱,金兰新,韦新荣. 子宫颈鳞癌雌、孕激素受体表达及其与淋巴结转移的关系研究[J]. 新疆医科大学学报, 1997, 0(1)
作者姓名:古丽娜  陈晓  拉莱  金兰新  韦新荣
作者单位:Departmetn of Pathology,Xinjiang Medical College
摘    要:应用免疫组化技术检测46例子宫颈癌雌激素受体(ER)和孕激素受体(PR)表达及其与淋巴结转移的关系。结果表明:宫颈癌ER阳性率为41.3%(19/46),PR阳性率为52.2%(24/46),两者均阳性为26.1%(12/46)。ER及PR在宫颈癌表达无显著性差异。ER或PR阳性的子宫颈癌其淋巴结转移率22.6%(7/31),而ER和PR均阴性其淋巴结转移率为53.3%(8/15)。两者转移率有显著性差异(P<0.05)。

关 键 词:子宫颈癌  雌激素受体  孕激素受体  癌转移

Immunohistochemical Study on the Expression of ER and PR of Cervical Squamous Cell Carcinoma and the Relation to Tumor Metastasis in Lymphnodes
Gulina,Chen Xiao, Lalai et al. Immunohistochemical Study on the Expression of ER and PR of Cervical Squamous Cell Carcinoma and the Relation to Tumor Metastasis in Lymphnodes[J]. Journal of Xinjiang Medical University, 1997, 0(1)
Authors:Gulina  Chen Xiao   Lalai et al
Abstract:By using inmmunohistochemistry to detect the expression of ER and PR in cervical squa-mous cell carcinoma and relation to the tumor metastasis in resected lymphnodes were stud-ied. It showed that the immunostaining positive of ER and PR, and both were 41. 3% (19/46 )' 52. 5 % (24/46) and 21. 6 % (12/46) respectively. The metastatic rates in ER or/and PRpositive negative were 22. 6% (7/31) and 53. 3% (8/15) (P<0. 05)respectively. It suggestedthat the expression of ER and PR of cervical carcinoma could be used to predict the prognosisand to evaluate the result of treatment in these patients.
Keywords:cervical carcinoma  tumor metastasis  estrogen receptor (ER)  progesterone receptor (PR)
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