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角膜缘上皮移植治疗化学伤和热烧伤后的眼球表面疾患
引用本文:韩真真,陈峰.角膜缘上皮移植治疗化学伤和热烧伤后的眼球表面疾患[J].中国实用眼科杂志,1998,16(12):736-737.
作者姓名:韩真真  陈峰
作者单位:温州医学院附属第二医院
摘    要:本文采用自体或异体角膜缘上皮移植治疗8例(8眼)化学伤和热烧伤后角膜表面缺损及血管翳性混浊。结果:8例中,上皮稳定愈合7例,角膜透明6例(其中包括1例行Ⅱ期穿透性角膜移植术),视力均有明显提高。结论:采用自体或异体角膜缘上皮移植替换严重受损的角膜缘组织,通过供体干细胞的增殖、分化能有效地修复和稳定受损的角膜表面,是治疗单侧或双侧眼球表面疾患的合理治疗方法

关 键 词:角膜缘上皮移植  干细胞  眼灼伤

The transplantation of auto or hetero corneal limbus epithelium for treating the severe disease of eyeball surface by chemical and thermic burns
Han Zhen zhen,Chen Feng,Zheng Sui lian.The transplantation of auto or hetero corneal limbus epithelium for treating the severe disease of eyeball surface by chemical and thermic burns[J].Chinese Journal of Practical Ophthalmology,1998,16(12):736-737.
Authors:Han Zhen zhen  Chen Feng  Zheng Sui lian
Abstract:The second affilated hospital of Wen Zhou medical college Wen Zhou 325000 Ocular chemical and thermic burns are severe ocular injuries,limbal epithelial autograf or allogeneic transplantation was performed on 8 cases (8 eyes) with vascularized corneal opacity and ocular surface defect by chemical and thermic burns.Results:Visual acuity was improved in 8 cases,the epithelial healing was stable in 7 cases,and there was corneal graft transparency in 6 cases.Conclusion:epithelial autograf or allogeneic transplantation can be applied to repair defect surface of eyeball through replacement ofinjured limbus by means of proliferation and differentiation from donors stem cells,it is a reasonable therapy method for unilateral or biliateral disease of ocular surface.
Keywords:transplantation  corneal  limbus  epithelium  Stem  cell  Ocular  burns  
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