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Single-dose,subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label,multicentre, phase 1 dose-escalation trial
Authors:Nicola Longo  Cary O Harding  Barbara K Burton  Dorothy K Grange  Jerry Vockley  Melissa Wasserstein  Gregory M Rice  Alejandro Dorenbaum  Jutta K Neuenburg  Donald G Musson  Zhonghua Gu  Saba Sile
Affiliation:1. University of Utah, Salt Lake City, UT, USA;2. Oregon Health & Sciences University, Portland, OR, USA;3. Ann and Robert H Lurie Children''s Hospital and Northwestern University Feinberg School of Medicine, Chicago, IL, USA;4. Washington University School of Medicine, St Louis, MO, USA;5. University of Pittsburgh School of Medicine, PA, USA;6. Mount Sinai School of Medicine, New York, NY, USA;g University of Wisconsin, Madison, WI, USA;h BioMarin Pharmaceutical, Novato, CA, USA
Abstract:
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