Neurocognitive indices of executive hypercontrol in obsessive-compulsive disorder |
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Authors: | Bucci P Galderisi S Catapano F Di Benedetto R Piegari G Mucci A Maj M |
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Affiliation: | Department of Psychiatry, University of Naples SUN, Naples, Italy. paola.bucci@unina2.it |
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Abstract: | OBJECTIVE: Cognitive impairment, more often involving memory and/or executive functions, has been reported in obsessive-compulsive (OC) patients. The present study aimed at: i) replicating, in an independent sample, previous findings by our group showing neurocognitive slowness limited to executive tasks; ii) assessing the influence of deficit in general cognitive abilities on executive dysfunction. METHOD: A comprehensive neuropsychological battery was administered to 30 drug-free OC patients and 30 healthy controls. RESULTS: Obsessive-compulsive patients performed worse on visuospatial tests, were slower on executive tasks, and performed worse on the Wisconsin Card Sorting Test. After covarying for Wechsler Adult Intelligence Scale-Revised performance Intellectual Quotient, a lesser degree of executive dysfunction was observed. CONCLUSION: Obsessive-compulsive patients exhibit an impairment of executive functions, especially when tasks also require visuospatial abilities. The impairment might reflect a hyperactivity of the executive control. |
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Keywords: | obsessive–compulsive disorder neuropsychological tests prefrontal cortex depressive symptoms |
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