Cultural adaptation and application of the IBS–QOL in China:
a disease-specific quality-of-life questionnaire |
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Authors: | Wen-wei Huang Fu-sheng Zhou Donald M Bushnell Chiaka Diakite Xiao-huan Yang |
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Institution: | (1) Piwei Institute, Guangzhou University of Chinese Medicine, 12#, Jichang Road, Guangzhou City, Guangdong Province, 510405, China;(2) Piwei Institute, Guangzhou University of Chinese Medicine, Guangdon, China;(3) Health Research Associates, Inc., Mountlake Terrace, Washington, USA;(4) National Institute of Research on Public Health Department of Traditional Medicine, Bamako, Mali;(5) School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China |
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Abstract: | Background
Irritable bowel syndrome (IBS) is a chronic and episodic illness characterized by altered bowel habits and associated abdominal
pain. At present, IBS is one of the most common functional gastrointestinal and motility disorders affecting countries around
the world. Surveys have found that patients with IBS have a significantly lower health-related quality of life.
Objectives
The aim of this study was to translate and examine the validity of the Irritable Bowel Syndrome–Quality of Life questionnaire
(IBS–QOL) in patients suffering from IBS in China.
Methods
A structured procedure was used for the translation and cultural adaptation of the original English IBS–QOL into Chinese.
The questionnaire was administered to 73 clinical patients with IBS and␣70 healthy individuals. Psychometric testing for reliability,
validity and responsiveness followed standardized procedures. Test–retest reliability (10–20 hours) was assessed using the
clinical patients. Follow-up (4 weeks) was collected for 61 clinical patients. All enrolled patients also completed the Short
Form-36 Health Survey (SF-36) at the baseline visit. Responsiveness to treatment (Venlafaxine and traditional Chinese herbal
medicine) was assessed by one-way ANOVA methods.
Results
The average length of time required to complete the questionnaire was short (5.63 min for IBS patients and 5.54 min for healthy
subjects by self-administration). Internal consistency (Cronbach’s alpha) values ranged from 0.722 to 0.914 for the Chinese
IBS–QOL subscales and test–retest reliability coefficients were higher than 0.920 on all subscales. The convergent and discriminate
validity results comparing the Chinese translation of the IBS–QOL overall score and the SF-36 subscales confirmed our predicted
hypotheses. The Chinese IBS–QOL scores are more highly correlated with social functioning, vitality and general health (SF-36)
and show weaker associations with physical functioning, role physical, mental health, and bodily pain (SF-36). The Chinese
translation of the IBS–QOL was responsive to treatment.
Conclusion
In general, the Chinese translation of the IBS–QOL, after cultural adaptation and revision, possesses good reliability, validity
and responsiveness. It is a reliable and valid instrument to assess the quality of life in Chinese patients suffering from
IBS and is an appropriate measure to use in further clinical trials or for related research projects in China. |
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Keywords: | Chinese translation of the IBS– QOL Quality of life IBS Reliability Validity Responsiveness |
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