秃发性毛发角化症

报告1例秃发性毛发角化症。患者女，22岁。因全身泛发毛囊性红色丘疹8年，头皮瘢痕性秃发伴瘙痒4年就诊。临床表现为头部毛发稀疏，部分秃发区可见毛囊萎缩。面颊部毛细血管扩张，密集毛囊性粉刺样丘疹，四肢、躯干泛发粟米大毛囊性丘疹。枕部头皮组织病理检查：表皮角化过度，表皮突局灶性延长，毛囊口有角质栓，毛囊内外根鞘灶性萎缩或消失，局部多核巨细胞反应性增生，毛囊周围及真皮血管周围见较多淋巴细胞浸润。诊断：秃发性毛发角化症。

A case of keratosis pilaris decalvans

A case of keratosis pilaris decalvans is described. A 22-year-old female patient presented with 8 years history of small, acuminate, follicular red papules widespread, and 4 years history of pruritic atrophic atrichia. Clinical examination showed scalp hair was thin. Atrophic atrichia was found on some alopecia area. Millet-papilla and dilatated capillary were seen in the jowl. Follicular horny plug papules were widespread. Histopathology examination showed hyperkeratosis of the epidermis and focal prolong epidermis ridges. There was a muhinuclear giant cell responsive hyperplasia, instead of focal atrophy or disappearance of follicular root sheath. And lymphocytes infiltration around hair follicle and derma blood vessel was prominent. This case was diagnosed as a keratosis pilaris decalvans based on clinical data and histological examination.