伴有发汗异常的Holmes-Adie综合征(附1例报告)

目的探讨Holmes-Adie综合征(HAS)的临床表现、病理特点及发病机制。方法对1例伴有发汗异常的HAS患者的临床资料结合文献进行分析。结果该患者具有典型的Adie瞳孔、下肢腱反射消失等HAS临床表现及发汗过多等自主神经功能异常症状,眼科裂隙灯检查证实为HAS特征性瞳孔;头颅MRI示腔隙性脑梗死;瞳孔睫状神经节部分性或完全性失神经是HAS主要病理特点。结论HAS病因不明,具有特征性瞳孔表现,与自主神经功能异常有一定关联,需与Ross综合征及Harlequin综合征等疾病相鉴别。

Holmes-Adie syndrome with sweating abnormality (report of 1 case)

Objective To investigate the clinical manifestation, pathological features and pathogenesis of Holmes-Adie syndrome (HAS). Methods The clinical data of one HAS patient with sweating abnormality and combined with literatures were analysed. Results The patient had the typical characteristics of HAS, including Adie pupil, areflexia of lower limb and the symptoms of autonomic nerve dysfunction. The characteristic pupil of HAS was proved by slit lamp of ophthalmology. Cranial MRI showed lacunar infarction. A par...